Genetic compatibility test
Genetic compatibility testing, also known as ‘genetic matching,’ consists of a genetic study to minimise the transmission of genetic diseases to offspring, as it can identify altered genes and detect whether there are any mutations in common between the couple.
There are currently more than 7,000 genetic diseases, which are responsible for 1-2 out of every 100 babies born suffering from these serious conditions.
We are all carriers of an average of 2 to 5 mutations that cause rare, potentially serious diseases, which we can pass on to our offspring. Read more about the rare disease listeriosis. In most cases, we are unaware of this, as carriers generally do not show symptoms of the disease.
Being a carrier of these mutations does not necessarily mean that you will suffer from the disease, but there is a possibility that your children will suffer from it if your partner is also a carrier of mutations in the same gene. In this case, the probability of having an affected child would be 25%.
What Is a Genetic Compatibility Test?
The main goal of the Genetic Compatibility Test is to determine whether both partners carry the same mutation in the same gene. Sharing such a mutation significantly increases the risk of transmitting a genetic disease to the offspring.
How Is the Genetic Compatibility Test Performed?
This is a simple blood test that can be performed at any specialized genetics laboratory. For your convenience, it can also be done at our facilities.
After a consultation with the doctor, a blood sample will be taken and sent to a certified reference genetics lab. The results are usually available within approximately two weeks.
Once the complete report arrives, your doctor will review the results with you and assess any potential genetic risks.
What Happens If I’m a Carrier?
If both partners are carriers of mutations in the same gene, it is strongly recommended to consult with a fertility specialist. In such cases, there are options to minimize the risk of passing the disorder to your child.
One such option is Preimplantation Genetic Diagnosis (PGD), a technique available at fertility clinics to ensure only healthy embryos are selected for transfer.
What Is Preimplantation Genetic Diagnosis (PGD)?
PGD is a genetic study performed on embryos before transfer during an IVF cycle. A few cells are extracted from each embryo to examine them for chromosomal or genetic abnormalities. Only healthy embryos are selected for implantation, reducing the risk of inherited diseases.
Who Should Consider a Genetic Compatibility Test?
This test is recommended for anyone planning a pregnancy, but it is especially beneficial for:
- Couples or single women undergoing assisted reproductive treatments.
- Individuals with a family history of genetic or reproductive disorders.
- Anyone seeking additional information about the risk of transmitting genetic conditions to their children.
For more tips on assisted reproduction, you can also read our 10 fertility recommendations [link to article if available].